Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | IAPP | P10997 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720593 | 0.82 | ALDH1A1 (0.39) | IAPPCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11720586 | 0.82 | ALDH1A1 (0.39) | IAPPCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL129081 | 0.77 | CES2 (0.38) | IAPPCES2CES1FFAR3HDAC3 | |
| SCHEMBL14249906 | 0.77 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL18507648 | 0.77 | ALDH1A1 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18507649 | 0.77 | ALDH1A1 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11238794 | 0.77 | — | — | |
| SCHEMBL14969570 | 0.77 | — | — | |
| SCHEMBL27311427 | 0.76 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10871136 | 0.75 | CES2 (0.50) | PPARGPPARAIAPPTRPA1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| EP-0634994-A1 | ALDOLISATION-DEHYDRATION PROCESS | Kvaerner Process Technology Limited (GB) | 1995-01-25 | — | — | EP | disclosed |