Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12499555 | 0.98 | LMNA (0.47) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL3174714 | 0.87 | LOXL2 (0.61) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL14967252 | 0.85 | CYP4A11 (0.55) | LOXL2GAATSHRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL12499723 | 0.85 | LOXL2 (0.59) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL15498466 | 0.85 | KDM4E (0.45) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL23582661 | 0.84 | ALDH1A1 (0.46) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL4451323 | 0.84 | TSHR (0.47) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL8002537 | 0.84 | GAA (0.63) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL5502090 | 0.83 | ALDH1A1 (0.49) | LOXL2GAATSHRKDM4EALDH1A1 | |
| SCHEMBL2742567 | 0.83 | TSHR (0.61) | GAATSHRKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038284-A2 | HETEROBICYLIC METALLOPROTEASE INHIBITORS | Alantos Pharmaceuticals, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1981855-A2 | SUBSTITUTED BIS-AMIDE METALLOPROTEASE INHIBITORS | Alantos Pharmaceuticals Holding, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007139860-A2 | HETEROBICYLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007079199-A2 | SUBSTITUTED BIS-AMIDE METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, HOLDING, INC. (US) | 2007-07-12 | — | — | WO | disclosed |