Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658322 | 0.81 | DHODH (0.44) | KIF11 | |
| SCHEMBL3655842 | 0.80 | KIF11 (0.41) | KIF11 | |
| SCHEMBL24386393 | 0.68 | HPGD (0.61) | — | |
| SCHEMBL30810730 | 0.66 | KIF11 (0.53) | KIF11 | |
| SCHEMBL3660215 | 0.66 | P2RX3 (0.59) | — | |
| SCHEMBL3660070 | 0.66 | DHODH (0.45) | — | |
| SCHEMBL19407439 | 0.65 | MLYCD (0.58) | KIF11 | |
| SCHEMBL10243692 | 0.65 | P2RX3 (0.69) | — | |
| SCHEMBL3660906 | 0.64 | DHODH (0.43) | AKR1C3 | |
| SCHEMBL3657018 | 0.63 | DHODH (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008000645-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |