SCHEMBL1886992

SCHEMBL1886992

Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1NC(=O)c1c(I)cccc1C(=O)NC(C)(C)CS(C)(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.36
MAPT P10636 4/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPK1 P28482 2/20 0.34
GFER P55789 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
LMNA P02545 2/20 0.33
NPC1 O15118 1/20 0.33
ALOX15 P16050 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PLA2G7 Q13093 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
SCN9A Q15858 1/20 0.33
RXFP1 Q9HBX9 3/20 0.33
GAA P10253 2/20 0.33
TLR8 Q9NR97 1/20 0.33
TLR7 Q9NYK1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flubendiamide SCHEMBL29369179 0.96 EPHX2 (0.36) EPHX2MAPTALDH1A1MAPK1LMNA
Flubendiamide SCHEMBL4054589 0.96 EPHX2 (0.36) EPHX2MAPTALDH1A1MAPK1LMNA
Flubendiamide SCHEMBL27362 0.96 EPHX2 (0.36) EPHX2MAPTALDH1A1MAPK1LMNA
Flubendiamide SCHEMBL15798517 0.95 EPHX2 (0.35) EPHX2MAPTALDH1A1MAPK1LMNA
SCHEMBL19362074 0.94 PPARG (0.35) MAPTPLA2G7RXFP1GAAP2RX1
SCHEMBL13121150 0.93 MAPT (0.34) EPHX2MAPTALDH1A1MAPK1LMNA
SCHEMBL1886993 0.90 PPARG (0.37) LMNARAB9AHSD17B10PLA2G7RXFP1
SCHEMBL13612662 0.89 RXFP1 (0.36) EPHX2MAPTALDH1A1MAPK1LMNA
SCHEMBL15850708 0.89 RXFP1 (0.37) MAPTALDH1A1MAPK1LMNANPC1
SCHEMBL14076847 0.89 MAPT (0.35) MAPTALDH1A1MAPK1LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2303007-B1 PESTICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2016-02-10 EP claimed
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-28 US claimed
US-12161117-B2 Agrochemical combinations UPL LTD (IN) 2024-12-10 US disclosed
US-20240315243-A1 A COMBINATION OF FLUBENDIAMIDE AND SEAWEED EXTRACT PI INDUSTRIES LTD. (IN) 2024-09-26 US disclosed
US-11812748-B2 Pesticidal combinations UPL LTD (IN) 2023-11-14 US disclosed
US-11191271-B2 Active compound combinations having insecticidal/acaricidal properties BAYER AKTIENGESELLSCHAFT (DE) 2021-12-07 US disclosed
EP-2303007-B2 PESTICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-13 EP disclosed
US-20210127680-A1 NOVEL AGROCHEMICAL COMBINATIONS UPL LTD (IN) 2021-05-06 US disclosed
US-20200236937-A1 ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL/ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2020-07-30 US disclosed
US-20200138025-A1 NOVEL PESTICIDAL COMBINATIONS UPL LTD (IN) 2020-05-07 US disclosed
US-20170311605-A1 SYNERGISTIC BACILLUS THURINGIENSIS SUBSP. AIZAWAI AND FLUBENDIAMIDE MIXTURES FOR DIAMONDBACK MOTH, BEET ARMYWORM, SOYBEAN LOOPER, CORN EARWORM, AND SUGARCANE BORER CONTROL VALENT BIOSCIENCES LLC 2017-11-02 US disclosed
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-28 US disclosed
US-20080194599-A1 Method of Mollusc Control SYNGENTA CROP PROTECTION, INC. (US) 2008-08-14 US disclosed
US-20080145349-A1 Composition for noxious organisms-controlling agent and method for using the same NIHON NOHYAKU CO., LTD. (JP) 2008-06-19 US disclosed
US-20080064736-A1 Substituted 2-Pyrrolidone Derivatives as Fungicides and Insecticides BAYER CROPSCIENCE AG (DE) 2008-03-13 US disclosed
US-20080021045-A1 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action BAYER CROPSCIENCE AKTIENGESELLSCHSFT (DE) 2008-01-24 US disclosed
US-20070293514-A1 Triazolopyrimidines BAYER CROPSCIEMCE AG (DE) 2007-12-20 US disclosed
US-20070275967-A1 Pyrazolinols BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-11-29 US disclosed
US-20070259893-A1 microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-11-08 US disclosed
US-20070219199-A1 Use of Sulfonanilides as Agricultural and Horticultural Fungicide BAYER CROPSCIENCE AG (DE) 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194599-A1 Method of Mollusc Control PTMA, PIR, FLNB EPHX2 1609/4885MAPT 3785/4885ALDH1A1 3966/4885
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides ATL3, RPL30, MLN EPHX2 1035/4885MAPT 889/4885ALDH1A1 4634/4885
US-11812748-B2 Pesticidal combinations DDT, BCHE, QDPR EPHX2 1449/4885MAPT 4063/4885ALDH1A1 4209/4885
US-20240315243-A1 A COMBINATION OF FLUBENDIAMIDE AND SEAWEED EXTRACT ACHE, DDT, ARF4 EPHX2 1908/4885MAPT 1192/4885ALDH1A1 1477/4885
US-20070275967-A1 Pyrazolinols RRS1, RECQL, PNISR EPHX2 2681/4885MAPT 3728/4885ALDH1A1 2701/4885
US-20200138025-A1 NOVEL PESTICIDAL COMBINATIONS DDT, BCHE, PDE1B EPHX2 1438/4885MAPT 4227/4885ALDH1A1 4310/4885
US-20070293514-A1 Triazolopyrimidines QDPR, DPYD, Q6ZSR9 EPHX2 1269/4885MAPT 2728/4885ALDH1A1 1155/4885
US-12161117-B2 Agrochemical combinations DDT, ACHE, BCHE EPHX2 1137/4885MAPT 1698/4885ALDH1A1 1510/4885
US-20080021045-A1 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action Q6ZSR9, CYP3A7, CYP4X1 EPHX2 1492/4885MAPT 3520/4885ALDH1A1 334/4885
US-20210127680-A1 NOVEL AGROCHEMICAL COMBINATIONS DDT, ACHE, UCHL3 EPHX2 1238/4885MAPT 2091/4885ALDH1A1 1920/4885
US-20070219199-A1 Use of Sulfonanilides as Agricultural and Horticultural Fungicide CBR3, CYP51A1, CBR1 EPHX2 2345/4885MAPT 4582/4885ALDH1A1 1037/4885
US-20080064736-A1 Substituted 2-Pyrrolidone Derivatives as Fungicides and Insecticides DDT, PPM1F, PPM1D EPHX2 3666/4885MAPT 2036/4885ALDH1A1 1151/4885
US-11191271-B2 Active compound combinations having insecticidal/acaricidal properties ACHE, CYP51A1, ACAT1 EPHX2 455/4885MAPT 2012/4885ALDH1A1 541/4885
US-20080145349-A1 Composition for noxious organisms-controlling agent and method for using the same C1S, CRYZ, CRYAA EPHX2 888/4885MAPT 1391/4885ALDH1A1 1997/4885
US-20200236937-A1 ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL/ACARICIDAL PROPERTIES ACHE, CYP51A1, ACAT1 EPHX2 455/4885MAPT 2012/4885ALDH1A1 541/4885
US-20070259893-A1 microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms PNPO, CYP4X1, CYP1B1 EPHX2 1374/4885MAPT 3611/4885ALDH1A1 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.