SCHEMBL4055008

SCHEMBL4055008

CC(C)(C)OC(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.57
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
MAPT P10636 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CA2 P00918 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2A6 P11509 1/20 0.46
PTPN7 P35236 1/20 0.45
MMP1 P03956 2/20 0.44
MMP12 P39900 1/20 0.44
KDM4E B2RXH2 1/20 0.44
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
FABP7 O15540 1/20 0.43
FABP3 P05413 1/20 0.43
BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4061539 0.93 ELANE (0.65) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL4058745 0.83 NCEH1 (0.58) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL14564205 0.83 ELANE (0.48) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL1809377 0.83 KMT2A (0.66) KMT2AMEN1MAPTTDP1CA2
SCHEMBL4061370 0.81 ELANE (0.81) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL13845254 0.81 ELANE (0.51) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL948124 0.81 ALDH1A1 (0.49) ELANEKMT2AMEN1CA2ALDH1A1
SCHEMBL14514195 0.80 KMT2A (0.58) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL18470649 0.80 ELANE (0.50) ELANEMAPTCA2L3MBTL1ALDH1A1
SCHEMBL17598755 0.80 ELANE (0.58) ELANEKMT2AMAPTCA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160074853-A1 LIGAND, NICKEL COMPLEX COMPRISING THE LIGAND, AND REACTION USING THE NICKEL COMPLEX NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2016-03-17 US disclosed
US-20090130419-A1 FOAM SHEET AND PRODUCTION PROCESS THEREOF OJI PAPER CO., LTD (JP) 2009-05-21 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-20080070998-A1 Foam Production Method OJI PAPER CO., LTD. (JP) 2008-03-20 US disclosed
EP-1795553-A1 PROCESS FOR PRODUCING FOAM Oji Paper Co., Ltd. (JP) 2007-06-13 EP disclosed
US-20060210785-A1 Foamed product in a sheet form and method for production thereof OJI PAPER CO., LTD. (JP) 2006-09-21 US disclosed
EP-1441256-B1 Radiation-sensitive resin composition JSR CORP (JP) 2006-05-31 EP disclosed
EP-1647570-A1 FOAMED PRODUCT IN A SHEET FORM AND METHOD FOR PRODUCTION THEREOF Oji Paper Co., Ltd. (JP) 2006-04-19 EP disclosed
EP-0789278-B1 Radiation-sensitive resin composition JSR CORP (JP) 2005-05-04 EP disclosed
US-6692887-B1 COPOLYMER OF SUCH AS MALEIC ANHYDRIDE AND NORBORNENE ACID CLEAVABLE DERIVATIVE; TRANSPARENCY; DRY ETCHING RESISTANCE; PHOTORESIST PATTERN WITH HIGH ADHESION, SENSITIVITY, RESOLUTION AND DEVELOPABILITY JSR CORPORATION (JP) 2004-02-17 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
EP-0541112-B1 Positive type light-senstitive composition FUJI PHOTO FILM CO LTD (JP) 2001-09-05 EP disclosed
EP-0249139-B2 Resist compositions and use MICROSI INC (US) 1998-03-11 EP disclosed
EP-0789278-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-08-13 EP disclosed
US-5362607-A Photo-patternable in absence of moisture; treating substrate with positive resist composition, baking, irradiating resist in patterned way, heating, developing; resist of water-soluble phenolic resin, tertiary butyl compound, aryl onium salt MICROSI, INC. (US) 1994-11-08 US disclosed
US-5310619-A Resist compositions comprising a phenolic resin, an acid forming onium salt and a tert-butyl ester or tert-butyl carbonate which is acid-cleavable MICROSI, INC. (US) 1994-05-10 US disclosed
EP-0541112-A1 Positive type light-senstitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-05-12 EP disclosed
EP-0249139-A2 Resist compositions and use MicroSi, Inc. (a Delaware corporation) (US) 1987-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160074853-A1 LIGAND, NICKEL COMPLEX COMPRISING THE LIGAND, AND REACTION USING THE NICKEL COMPLEX NISCH, DDT, TEC ELANE 1846/4885KMT2A 2140/4885MEN1 1615/4885
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ELANE 422/4885KMT2A 1062/4885MEN1 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.