SCHEMBL4055044

SCHEMBL4055044

Cc1cc(O)ccc1Cc1cc(C)c(O)c(Cc2ccc(O)cc2C)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.53
ALOX5 P09917 1/20 0.40
ESR2 Q92731 4/20 0.39
ESR1 P03372 3/20 0.39
HMGB1 P09429 1/20 0.39
CXCL12 P48061 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
AMY1A P0DUB6 1/20 0.36
HSD17B1 P14061 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4063920 0.93 SHBG (0.43) SHBGALOX5ESR2ESR1MEN1
SCHEMBL28694041 0.91 SHBG (0.48) SHBGALOX5ESR2ESR1HMGB1
SCHEMBL4055487 0.88 ALOX5 (0.54) SHBGALOX5MEN1MAPTKMT2A
SCHEMBL31181945 0.85 SHBG (0.56) SHBGALOX5ESR2ESR1HMGB1
SCHEMBL30374543 0.85 SHBG (0.56) SHBGALOX5ESR2ESR1HMGB1
SCHEMBL3177884 0.85 SHBG (0.56) SHBGALOX5ESR2ESR1HMGB1
SCHEMBL13609036 0.84 CA1 (0.45) SHBGESR2ESR1AMY1AHSD17B1
SCHEMBL69172 0.83 ESR2 (0.49) ALOX5ESR2ESR1HSD17B1
SCHEMBL4062078 0.83 ALOX5 (0.49) SHBGALOX5MEN1MAPTKMT2A
SCHEMBL3710965 0.82 SHBG (0.61) SHBGALOX5ESR2ESR1HMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM SHBG 3960/4885ALOX5 576/4885ESR2 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.