SCHEMBL4055135

SCHEMBL4055135

CCC1=C(C)c2c(-c3ccccc3)cccc2C1(Cl)[SiH2]C1(Cl)C(CC)=C(C)c2c(-c3ccccc3)cccc21.[Zr]

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
SLC6A3 Q01959 1/20 0.31
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7706377 0.88 PSMB5 (0.33) PDCD1CD274
SCHEMBL6464431 0.83 PDCD1 (0.33) PDCD1CD274SLC6A3
SCHEMBL1531948 0.83 PDCD1 (0.33) PDCD1CD274SLC6A3
SCHEMBL4064036 0.81
SCHEMBL4062476 0.81 CYP2D6 (0.33)
SCHEMBL1775470 0.80 PDCD1 (0.33) PDCD1CD274SLC6A3
SCHEMBL7614959 0.78 SLC6A2 (0.32) SLC6A3
SCHEMBL4061870 0.77 SLC6A2 (0.32) SLC6A3
SCHEMBL4312122 0.74 CNR2 (0.32)
SCHEMBL20474530 0.74 PTGS1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7205363-B2 Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-04-17 US claimed
WO-2005003184-A1 POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-13 WO claimed
US-20040254316-A1 Polymerization processes using antistatic agents EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-16 US claimed
US-6664348-B2 Metallocene catalyst such as dimethylsilandiylbis(2-ethyl-4-phenyl-1-indenyl)zirconium dimethyl for polymerization of propylene EXXONMOBIL CHEMICAL PATENTS INC. 2003-12-16 US claimed
US-6524988-B2 Metallocene, an activator and a fluorided support; polymerization catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2003-02-25 US claimed
US-20020169261-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-11-14 US claimed
US-20020160914-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-10-31 US claimed
EP-2045304-B1 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC (US) 2017-10-11 EP disclosed
US-7579416-B2 Catalyst system for olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2009-08-25 US disclosed
EP-2045304-A2 Polypropylene-Based Adhesive Compositions ExxonMobil Chemical Patents Inc. (US) 2009-04-08 EP disclosed
EP-1311593-B1 POLYPROPYLENE FILMS EXXONMOBIL CHEM PATENTS INC (US) 2009-01-07 EP disclosed
US-7205363-B2 Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-04-17 US disclosed
EP-1315858-B1 POLYPROPYLENE FIBERS AND FABRICS EXXONMOBIL CHEM PATENTS INC (US) 2007-02-07 EP disclosed
US-20020019507-A1 Polypropylene-based adhesive compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-02-14 US disclosed
US-20010049331-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2001-12-06 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed
US-20010039314-A1 Propylene polymers for films EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-08 US disclosed
WO-2001036497-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001036499-A1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001032757-A1 FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-05-10 WO disclosed