SCHEMBL1775470

SCHEMBL1775470

CC1=C(C)C(Cl)([SiH2]C2(Cl)C(C)=C(C)c3c(-c4ccccc4)cccc32)c2cccc(-c3ccccc3)c21.[Ti]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
SLC6A3 Q01959 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1531948 0.97 PDCD1 (0.33) PDCD1CD274SLC6A3SLC6A2SLC6A4
SCHEMBL6464431 0.97 PDCD1 (0.33) PDCD1CD274SLC6A3SLC6A2SLC6A4
SCHEMBL4061870 0.90 SLC6A2 (0.32) SLC6A3SLC6A2SLC6A4
SCHEMBL4064323 0.81 HDAC4 (0.38) SLC6A3SLC6A2SLC6A4CYP2A6
SCHEMBL4320533 0.81 PDK2 (0.33)
SCHEMBL7614959 0.80 SLC6A2 (0.32) SLC6A3SLC6A2SLC6A4
SCHEMBL4055135 0.80 PDCD1 (0.33) PDCD1CD274SLC6A3
SCHEMBL3353069 0.79 PDK2 (0.33)
SCHEMBL3354011 0.79 S100A4 (0.33)
SCHEMBL5951511 0.78 PDK2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410231-B2 Production process of olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-02 US disclosed
US-7943715-B2 Polymerization of 1,6-heptadiene in the presence of a catalyst formed by contacting a transition metal with a diimino aluminum or boron compound, giving a polymer structure of alternating ethylene and cyclopentene; superior balance between a heat resistance and workability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-17 US disclosed
US-20100029868-A1 PRODUCTION PROCESS OF OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-04 US disclosed
US-20080234450-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-25 US disclosed
US-20080221286-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
US-20080214754-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-20080214756-A1 CYCLIC OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
WO-2007023618-A1 HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-01 WO disclosed