SCHEMBL6464431

SCHEMBL6464431

CC1=C(C)[C@](Cl)([SiH2][C@@]2(Cl)C(C)=C(C)c3c(-c4ccccc4)cccc32)c2cccc(-c3ccccc3)c21.[Zr]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
SLC6A3 Q01959 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1531948 1.00 PDCD1 (0.33) PDCD1CD274SLC6A3SLC6A2SLC6A4
SCHEMBL1775470 0.97 PDCD1 (0.33) PDCD1CD274SLC6A3SLC6A2SLC6A4
SCHEMBL4061870 0.93 SLC6A2 (0.32) SLC6A3SLC6A2SLC6A4
SCHEMBL4320533 0.84 PDK2 (0.33)
SCHEMBL4064323 0.84 HDAC4 (0.38) SLC6A3SLC6A2SLC6A4CYP2A6
SCHEMBL7614959 0.83 SLC6A2 (0.32) SLC6A3SLC6A2SLC6A4
SCHEMBL4055135 0.83 PDCD1 (0.33) PDCD1CD274SLC6A3
SCHEMBL5951511 0.81 PDK2 (0.31)
SCHEMBL7706377 0.80 PSMB5 (0.33) PDCD1CD274
SCHEMBL6047509 0.79 PDCD1 (0.36) PDCD1CD274SLC6A3CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916886-B2 Propylene block copolymer JAPAN POLYPROPYLENE CORPORATION (JP) 2005-07-12 US disclosed