SCHEMBL1531948

SCHEMBL1531948

CC1=C(C)C(Cl)([SiH2]C2(Cl)C(C)=C(C)c3c(-c4ccccc4)cccc32)c2cccc(-c3ccccc3)c21.[Zr]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
SLC6A3 Q01959 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6464431 1.00 PDCD1 (0.33) PDCD1CD274SLC6A3SLC6A2SLC6A4
SCHEMBL1775470 0.97 PDCD1 (0.33) PDCD1CD274SLC6A3SLC6A2SLC6A4
SCHEMBL4061870 0.93 SLC6A2 (0.32) SLC6A3SLC6A2SLC6A4
SCHEMBL4320533 0.84 PDK2 (0.33)
SCHEMBL4064323 0.84 HDAC4 (0.38) SLC6A3SLC6A2SLC6A4CYP2A6
SCHEMBL7614959 0.83 SLC6A2 (0.32) SLC6A3SLC6A2SLC6A4
SCHEMBL4055135 0.83 PDCD1 (0.33) PDCD1CD274SLC6A3
SCHEMBL5951511 0.81 PDK2 (0.31)
SCHEMBL7706377 0.80 PSMB5 (0.33) PDCD1CD274
SCHEMBL6047509 0.79 PDCD1 (0.36) PDCD1CD274SLC6A3CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846770-B2 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-25 US claimed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US claimed
US-20220306792-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE CORNELL UNIVERSITY 2022-09-29 US disclosed
EP-4028432-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE Cornell University (US) 2022-07-20 EP disclosed
WO-2021051103-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE CORNELL UNIVERSITY (US) 2021-03-18 WO disclosed
US-9988323-B2 Catalyst BOREALIS AG (AT) 2018-06-05 US disclosed
EP-2746301-B1 Catalyst BOREALIS AG (AT) 2018-05-30 EP disclosed
EP-2935295-B1 CATALYST BOREALIS AG (AT) 2018-02-07 EP disclosed
US-20170137343-A1 Catalyst BOREALIS AG (AT) 2017-05-18 US disclosed
US-9598516-B2 Catalyst BOREALIS AG (AT) 2017-03-21 US disclosed
EP-2824107-B1 ANSA-METALLOCENE COMPOUND AND METHOD FOR PREPARING SUPPORTED CATALYST USING SAME LG CHEMICAL LTD (KR) 2017-01-18 EP disclosed
US-20020123582-A1 Highly active supported catalyst compositions SPECA ANTHONY N (US) 2002-09-05 US disclosed
US-6368999-B1 METALLOCENE POLYEMRIZATION CATALYST, ACTIVATOR, AND A SUPPORT THAT HAS BEEN FLUORIDED USING A FLUORIDE CONTAINING COMPOUND, REACTIVE FUNCTIONALITIES OF THE SUPPORT ARE REDUCED AND/OR DEACTIVATED EXXON MOBIL CHEMICAL PATENTS INC. 2002-04-09 US disclosed
WO-2002016480-A2 POLYPROPYLENE FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
WO-2002016455-A1 POLYPROPYLENE POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
US-20010051698-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2001-12-13 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed
US-20010039314-A1 Propylene polymers for films EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-08 US disclosed
US-6177526-B1 METALLOCENE; COCATALYST; MODIFIED OXIDE CONTAINS ORGANIC SILICON RADICALS CONTAINING AT LEAST ONE OF THE GROUPS NITROGEN, FLUORINE, PHOSPHORUS OR SULFUR. TARGOR GMBH (DE) 2001-01-23 US disclosed
US-5792819-A Process for the preparation of an olefin polymer TARGOR GMBH (DE) 1998-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137343-A1 Catalyst C5, POR, C9 PDCD1 4235/4885CD274 4042/4885SLC6A3 4157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.