Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 9/20 | 0.56 |
| ▸ | KCNJ5 | P48544 | 9/20 | 0.56 |
| ▸ | KCNJ3 | P48549 | 9/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303575 | 0.85 | MAPK14 (0.73) | KCNJ6KCNJ5KCNJ3MAPK14 | |
| SCHEMBL4297859 | 0.78 | MAPK14 (0.79) | KCNJ6KCNJ5KCNJ3MAPK14 | |
| SCHEMBL4056080 | 0.78 | KCNJ6 (0.53) | KCNJ6KCNJ5KCNJ3MAPK14EPHX2 | |
| SCHEMBL4298758 | 0.75 | MAPK14 (0.66) | KCNJ6KCNJ5KCNJ3MAPK14 | |
| SCHEMBL4295138 | 0.74 | MAPK14 (0.59) | KCNJ6KCNJ5KCNJ3MAPK14 | |
| SCHEMBL5189629 | 0.74 | KCNJ6 (0.49) | KCNJ6KCNJ5KCNJ3MAPK14MEN1 | |
| SCHEMBL5549530 | 0.73 | RAB9A (0.50) | KCNJ6KCNJ5KCNJ3MAPK14MEN1 | |
| SCHEMBL4052031 | 0.73 | KCNJ6 (0.60) | KCNJ6KCNJ5KCNJ3MAPK14EPHX2 | |
| SCHEMBL4049614 | 0.73 | MAPK14 (0.75) | MAPK14 | |
| SCHEMBL2081709 | 0.73 | MAPK14 (0.84) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836173-A4 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-1836173-A2 | ANTI-INFLAMMATORY MEDICAMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006081034-A2 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-08-03 | — | — | WO | disclosed |