Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.51 |
| ▸ | PLAU | P00749 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690463 | 0.88 | MEN1 (0.49) | ELANEPLAUF2NPC1GAA | |
| SCHEMBL4055641 | 0.87 | NPC1 (0.52) | NPC1GAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7745247 | 0.83 | ELANE (0.60) | ELANEPLAUF2GAAKDM4E | |
| SCHEMBL7745499 | 0.82 | KDM4E (0.52) | ELANEPLAUF2GAAKDM4E | |
| SCHEMBL29805554 | 0.81 | ELANE (0.54) | ELANEPLAUF2KDM4EALDH1A1 | |
| SCHEMBL26204710 | 0.80 | ELANE (0.59) | ELANEPLAUF2KDM4EALDH1A1 | |
| SCHEMBL13690853 | 0.80 | ELANE (0.64) | ELANEPLAUF2GAAKDM4E | |
| SCHEMBL4050207 | 0.78 | CNR1 (0.70) | NPC1GAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL13691111 | 0.78 | CNR1 (0.70) | NPC1GAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31429235 | 0.78 | ELANE (0.57) | ELANEPLAUF2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |