Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 8/20 | 0.51 |
| ▸ | PLAU | P00749 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12480155 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL12479194 | 0.86 | CFD (0.47) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL18953725 | 0.83 | ELANE (0.53) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL18953622 | 0.83 | MAPT (0.54) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL18953768 | 0.83 | ELANE (0.45) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL7745247 | 0.83 | ELANE (0.60) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL4055759 | 0.82 | ELANE (0.51) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL20589136 | 0.82 | NPSR1 (0.39) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL18953751 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL13329858 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |