Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.60 |
| ▸ | PLAU | P00749 | 3/20 | 0.60 |
| ▸ | F2 | P00734 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690853 | 0.88 | ELANE (0.64) | ELANEPLAUF2KDM4EALDH1A1 | |
| SCHEMBL26204710 | 0.85 | ELANE (0.59) | ELANEPLAUF2KDM4EALDH1A1 | |
| SCHEMBL1897336 | 0.84 | PTGER4 (0.59) | ELANEPLAUF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29781847 | 0.84 | HSD17B10 (0.61) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL12481560 | 0.84 | HSD17B10 (0.61) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL28726087 | 0.83 | HSD17B10 (0.65) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL31429235 | 0.83 | ELANE (0.57) | ELANEPLAUF2KDM4EALDH1A1 | |
| SCHEMBL15607599 | 0.83 | HSD17B10 (0.57) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4055759 | 0.83 | ELANE (0.51) | ELANEPLAUF2HSD17B10KDM4E | |
| SCHEMBL7745499 | 0.83 | KDM4E (0.52) | ELANEPLAUF2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |