Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367719 | 0.86 | TSHR (0.58) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL9145760 | 0.82 | TSHR (0.50) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL12602055 | 0.81 | TSHR (0.55) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL1285433 | 0.80 | CYP1A2 (0.45) | TSHRHSD17B10KMT2ALMNAALDH1A1 | |
| SCHEMBL28695618 | 0.80 | TSHR (0.60) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL889856 | 0.80 | TSHR (0.60) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL19859133 | 0.79 | LMNA (0.46) | TSHRHSD17B10LMNAALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL3920826 | 0.78 | TSHR (0.57) | TSHRHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL4847615 | 0.78 | ALDH1A1 (0.43) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL19616629 | 0.78 | TSHR (0.57) | TSHRHSD17B10KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140295328-A1 | CHAIN TRANSFER REAGENTS IN POLYURETHANE-BASED PHOTOPOLYMER FORMULATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-02 | — | — | US | claimed |
| EP-2766903-A1 | CHAIN TRANSFER REAGENTS IN POLYURETHANE-BASED PHOTOPOLYMER FORMULATIONS | Bayer Intellectual Property GmbH (DE) | 2014-08-20 | — | — | EP | claimed |
| CN-103875037-A | Chain transfer agents in polyurethane-based photopolymer compositions | BAYER IP GMBH | 2014-06-18 | — | — | CN | claimed |
| WO-2013053792-A1 | CHAIN TRANSFER REAGENTS IN POLYURETHANE-BASED PHOTOPOLYMER FORMULATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-18 | — | — | WO | claimed |
| CN-103396393-B | Glycerol levulinate ketals and uses thereof | AROMAGEN CORPORATION (US) | 2016-03-02 | — | — | CN | disclosed |
| EP-2356113-B1 | HETEROCYCLICALLY SUBSTITUTED ARYL COMPOUNDS AS HIF INHIBITORS | BAYER IP GMBH (DE) | 2015-01-07 | — | — | EP | disclosed |
| US-8906961-B2 | Glycerol levulinate ketals and their use in the manufacture of polyurethanes, and polyurethanes formed therefrom | SEGETIS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140295328-A1 | CHAIN TRANSFER REAGENTS IN POLYURETHANE-BASED PHOTOPOLYMER FORMULATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-2766903-A1 | CHAIN TRANSFER REAGENTS IN POLYURETHANE-BASED PHOTOPOLYMER FORMULATIONS | Bayer Intellectual Property GmbH (DE) | 2014-08-20 | — | — | EP | disclosed |
| CN-103875037-A | Chain transfer agents in polyurethane-based photopolymer compositions | BAYER IP GMBH | 2014-06-18 | — | — | CN | disclosed |
| CN-103396393-A | Glycerol levulinate ketals and use thereof | AROMAGEN CORP | 2013-11-20 | — | — | CN | disclosed |
| US-20130303648-A1 | GLYCEROL LEVULINATE KETALS AND THEIR USE IN THE MANUFACTURE OF POLYURETHANES, AND POLYURETHANES FORMED THEREFROM | GFBIOCHEMICALS LIMITED (MT) | 2013-11-14 | — | — | US | disclosed |
| EP-1954140-A2 | GLYCEROL LEVULINATE KETALS AND THEIR USE | Aromagen Corporation (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1675832-B1 | HETEROCYCLYL COMPOUNDS | GLAXO GROUP LTD (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2007062118-A2 | GLYCEROL LEVULINATE KETALS AND THEIR USE | AROMAGEN CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070060596-A1 | Heterocyclyl compounds | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | disclosed |
| US-20070060596-A1 | Heterocyclyl compounds | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | disclosed |
| US-20070060596-A1 | Heterocyclyl compounds | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | disclosed |
| EP-1675832-A1 | HETEROCYCLYL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005040128-A1 | HETEROCYCLYL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060596-A1 | Heterocyclyl compounds | F9, F12, CYP2C9 | TSHR 350/4885HSD17B10 3241/4885KMT2A 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.