Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056421 | 1.00 | CYP2C19 (0.50) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4237642 | 0.93 | ALDH1A1 (0.51) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4237644 | 0.93 | ALDH1A1 (0.51) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4059271 | 0.92 | CYP2C19 (0.54) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4059267 | 0.92 | CYP2C19 (0.54) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4058118 | 0.84 | ALDH1A1 (0.60) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4052735 | 0.81 | MAPT (0.57) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4052733 | 0.81 | MAPT (0.57) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4049726 | 0.80 | MAPT (0.52) | CYP2C19ALDH1A1MAPTGAAHTT | |
| SCHEMBL4049720 | 0.80 | MAPT (0.52) | CYP2C19ALDH1A1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111260-A1 | PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |