Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPY1R | P25929 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375239 | 0.76 | HRH3 (0.64) | ALDH1A1KCNH2HRH3BCHEACHE | |
| SCHEMBL5187226 | 0.76 | MAPT (0.54) | ACP1ALDH1A1L3MBTL1HTTKMT2A | |
| SCHEMBL4686979 | 0.74 | KMT2A (0.52) | ACP1ALDH1A1L3MBTL1HTTKMT2A | |
| SCHEMBL5178131 | 0.74 | ACP1 (0.46) | ACP1NPY1RHRH3CHEK2BCHE | |
| SCHEMBL3032322 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HTTKMT2AATM | |
| SCHEMBL6187060 | 0.71 | KMT2A (0.46) | ACP1KMT2ACHEK2 | |
| SCHEMBL5562096 | 0.71 | ACP1 (0.50) | ACP1HRH3KMT2ACHEK2 | |
| SCHEMBL11717409 | 0.71 | CHEK2 (0.42) | ACP1NPY1RKMT2ACHEK2 | |
| SCHEMBL5566839 | 0.71 | MAP2K1 (0.42) | ACP1CHEK2BCHEMAOAACHE | |
| SCHEMBL9219032 | 0.71 | ITGB3 (0.54) | L3MBTL1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | disclosed |