Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALAD | P13716 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812147 | 0.81 | PNMT (0.39) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5154542 | 0.77 | GPR35 (0.46) | DAOGPR35KDM4EALDH1A1MAPT | |
| SCHEMBL899479 | 0.77 | GSK3B (0.61) | DAOGPR35KDM4EALDH1A1MAPT | |
| Bromide SCHEMBL8935164 | 0.76 | GSK3B (0.59) | DAOGPR35KDM4EALDH1A1MAPT | |
| SCHEMBL21192466 | 0.76 | KMT2A (0.53) | DAOGPR35KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8935203 | 0.76 | GSK3B (0.59) | DAOGPR35KDM4EALDH1A1MAPT | |
| SCHEMBL25365859 | 0.74 | DAO (0.43) | DAOGPR35KDM4EALDH1A1MAPT | |
| SCHEMBL1529502 | 0.74 | DAO (0.63) | DAOGPR35KDM4EALDH1A1MAPT | |
| SCHEMBL28891536 | 0.74 | DAO (0.43) | DAOGPR35KDM4EALDH1A1MAPT | |
| SCHEMBL1529532 | 0.74 | DAO (0.63) | DAOGPR35KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252936-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2016067-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-08 | — | — | EP | disclosed |
| US-20090192175-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| EP-2016067-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007128410-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192175-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CYP1B1 | DAO 2583/4885GPR35 3022/4885KDM4E 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.