SCHEMBL4056593

SCHEMBL4056593

Cc1ccc(O)c(Cc2cc(Cc3cc(C)cc(Cc4cc(C)c(O)c(Cc5cc(C)ccc5O)c4)c3O)cc(C)c2O)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.75
SHBG P04278 1/20 0.49
HIF1A Q16665 5/20 0.44
CYP2C9 P11712 3/20 0.44
CYP2C19 P33261 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
HSPA5 P11021 2/20 0.40
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HSD17B10 Q99714 2/20 0.39
CYP2D6 P10635 1/20 0.39
TRPA1 O75762 1/20 0.37
HTT P42858 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 2/20 0.37
CYP3A4 P08684 2/20 0.37
HPGD P15428 2/20 0.37
ALOX15 P16050 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7546172 0.97 AMY1A (0.75) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL21096825 0.94 AMY1A (0.66) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL2386946 0.94 AMY1A (0.69) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL30320337 0.94 AMY1A (0.69) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL4059091 0.92 AMY1A (0.82) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL10136215 0.91 AMY1A (0.60) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL8078719 0.90 AMY1A (0.86) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL23864821 0.90 AMY1A (0.64) AMY1ASHBGHIF1ACYP2C9CYP2C19
SCHEMBL26290273 0.89 AMY1A (0.83) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL5364380 0.89 AMY1A (0.65) AMY1ASHBGHIF1AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9286753-A None JP disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
JP-H09286753-A PENTANUCLEAR NOVOLAK COMPOUND AND ITS USE SUMITOMO CHEM CO LTD 1997-11-04 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM AMY1A 2387/4885SHBG 3960/4885HIF1A 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.