Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 9/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056718 | 1.00 | KIF11 (0.41) | KIF11BRD4ADORA3NPSR1L3MBTL1 | |
| SCHEMBL4050591 | 0.98 | KIF11 (0.41) | KIF11BRD4ADORA3 | |
| SCHEMBL4055834 | 0.98 | KIF11 (0.41) | KIF11BRD4ADORA3 | |
| SCHEMBL4054974 | 0.95 | KIF11 (0.39) | KIF11BRD4ADORA3 | |
| SCHEMBL4054984 | 0.95 | KIF11 (0.39) | KIF11BRD4ADORA3 | |
| SCHEMBL4049089 | 0.90 | KIF11 (0.39) | KIF11BRD4ADORA3TLR7 | |
| SCHEMBL4252319 | 0.85 | BRD4 (0.39) | KIF11BRD4NPSR1L3MBTL1MAPT | |
| SCHEMBL4252323 | 0.85 | BRD4 (0.39) | KIF11BRD4NPSR1L3MBTL1MAPT | |
| SCHEMBL4056075 | 0.85 | KIF11 (0.40) | KIF11BRD4NPSR1L3MBTL1TLR7 | |
| SCHEMBL4056076 | 0.85 | KIF11 (0.40) | KIF11BRD4NPSR1L3MBTL1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070932-A1 | Pyrazolotriazines | 4SC AG (DE) | 2009-06-17 | — | — | EP | disclosed |