Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 13/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 13/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723548 | 0.74 | ADRA2B (0.84) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11332296 | 0.74 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AHTR1A | |
| SCHEMBL1724062 | 0.67 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1ATSHR | |
| SCHEMBL4054961 | 0.66 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CADRA1AHTR1A | |
| SCHEMBL4564280 | 0.66 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL14449748 | 0.65 | TAAR1 (0.42) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL10159872 | 0.65 | TAAR1 (0.40) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL2216731 | 0.65 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1ATAAR1 | |
| SCHEMBL1218576 | 0.64 | ADRA2A (0.67) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL15975257 | 0.63 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CADRA1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014168-A1 | Insecticidal heterocyclic compounds | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2014168-A1 | Insecticidal heterocyclic compounds | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008155031-A1 | HETEROCYCLIC COMPOUNDS FOR INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155031-A1 | HETEROCYCLIC COMPOUNDS FOR INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |