Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 6/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 6/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723548 | 0.92 | ADRA2B (0.84) | ADRA2AADRA2BADRA2CADRA1ALMNA | |
| SCHEMBL1218576 | 0.80 | ADRA2A (0.67) | ADRA2AADRA2BADRA2CADRA1ALMNA | |
| SCHEMBL13963571 | 0.77 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1ALMNA | |
| SCHEMBL11332296 | 0.77 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1ALMNA | |
| SCHEMBL1669616 | 0.75 | LMNA (1.00) | ADRA2AADRA2BADRA2CADRA1ALMNA | |
| SCHEMBL1669553 | 0.75 | LMNA (1.00) | ADRA2AADRA2BADRA2CADRA1ALMNA | |
| SCHEMBL4054961 | 0.74 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CADRA1ATSHR | |
| SCHEMBL6369306 | 0.74 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CADRA1ATSHR | |
| SCHEMBL2216731 | 0.73 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL3738928 | 0.73 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251453-A2 | Substituted amino-dihydrooxazoles, -thiazoles and -imidazoles, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-01-07 | — | — | EP | claimed |
| US-4256755-A | Method of using N-substituted dihydro-2-oxazolamines as analgesics | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1981-03-17 | — | — | US | claimed |
| US-8178567-B2 | Insecticidal substituted amino heterocyclic and heteroaryl derivatives | FMC CORPORATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178567-B2 | Insecticidal substituted amino heterocyclic and heteroaryl derivatives | FMC CORPORATION (US) | 2012-05-15 | — | — | US | disclosed |
| EP-1960369-B1 | INDANYL-AND TETRAHYDRONAPHTHYL-AMINO-AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| US-7981437-B2 | Indanyl- and tetrahydronaphthyl-amino-azoline compounds for combating animal pests | BASF SE (DE) | 2011-07-19 | — | — | US | disclosed |
| US-7981437-B2 | Indanyl- and tetrahydronaphthyl-amino-azoline compounds for combating animal pests | BASF SE (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100167925-A1 | Substituted Azolin-2-yl-Amino Compounds | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100137385-A1 | Insecticidal Substituted Amino Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| US-20100137385-A1 | Insecticidal Substituted Amino Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| US-20080293569-A1 | Indanyl- and Tetrahydronaphthyl-Amino-Azoline Compounds for Combating Animal Pests | BASF SE (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20080293569-A1 | Indanyl- and Tetrahydronaphthyl-Amino-Azoline Compounds for Combating Animal Pests | BASF SE (DE) | 2008-11-27 | — | — | US | disclosed |
| EP-1960369-A1 | INDANYL-AND TETRAHYDRONAPHTHYL-AMINO-AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008017649-A1 | SUBSTITUTED AZOLIN-2-YL-AMINO COMPOUNDS | BASF SE (DE) | 2008-02-14 | — | — | WO | disclosed |
| WO-2007093292-A2 | INSECTICIDAL SUBSTITUTED AMINO HETEROCYCLIC AND HETEROARYL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007060121-A1 | INDANYL-AND TETRAHYDRONAPHTHYL-AMINO-AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-05-31 | — | — | WO | disclosed |
| US-4861789-A | Dihydro-indene-amine-dihydrooxazoles | BEECHAM GROUP PLC (GB) | 1989-08-29 | — | — | US | disclosed |
| EP-0251453-A2 | Substituted amino-dihydrooxazoles, -thiazoles and -imidazoles, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-01-07 | — | — | EP | disclosed |
| US-4256755-A | Method of using N-substituted dihydro-2-oxazolamines as analgesics | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137385-A1 | Insecticidal Substituted Amino Heterocyclic and Heteroaryl Derivatives | DDT, AAAS, DDC | ADRA2A 194/4885ADRA2B 118/4885ADRA2C 124/4885 |
| US-20100167925-A1 | Substituted Azolin-2-yl-Amino Compounds | CBR3, NR2C2, HRH3 | ADRA2A 861/4885ADRA2B 446/4885ADRA2C 253/4885 |
| US-20080293569-A1 | Indanyl- and Tetrahydronaphthyl-Amino-Azoline Compounds for Combating Animal Pests | INMT, AIPL1, AADAT | ADRA2A 1392/4885ADRA2B 875/4885ADRA2C 669/4885 |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, COX6B1 | ADRA2A 2634/4885ADRA2B 2755/4885ADRA2C 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.