Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127594 | 1.00 | HTR2C (0.51) | HTR2CADRB2IDO1ARLMNA | |
| SCHEMBL19760706 | 0.79 | IDO1 (0.59) | HTR2CADRB2IDO1LMNAKDM4E | |
| SCHEMBL29611992 | 0.79 | IDO1 (0.59) | HTR2CADRB2IDO1LMNAKDM4E | |
| SCHEMBL3068128 | 0.76 | PRCP (0.54) | HTR2CADRB2ARHTR2AHTR2B | |
| SCHEMBL4307711 | 0.75 | SLC6A2 (0.56) | KDM4EATM | |
| SCHEMBL734917 | 0.73 | HTR2C (0.79) | HTR2CADRB2KDM4EATMHTR2A | |
| SCHEMBL3264403 | 0.73 | IDO1 (0.56) | HTR2CADRB2IDO1LMNAKDM4E | |
| SCHEMBL6215744 | 0.73 | HTR2C (0.47) | HTR2CADRB2IDO1LMNAKDM4E | |
| SCHEMBL31536293 | 0.73 | HTR2C (0.47) | HTR2CADRB2IDO1ARLMNA | |
| SCHEMBL2083374 | 0.73 | PLA2G6 (0.49) | IDO1LMNAKDM4EADRA1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106559-A1 | USES OF INDANE COMPOUNDS | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |
| CN-101472890-A | 3- (1H-indol- 3-ydindan-1-ylamine derivatives for the treatment of depression and anxiety | LUNDBECK & CO AS H (DK) | 2009-07-01 | — | — | CN | disclosed |