Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G6 | O60733 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.49 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625707 | 0.89 | ALDH1A1 (0.49) | PLA2G6MAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11676259 | 0.89 | ALDH1A1 (0.49) | PLA2G6MAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18554493 | 0.85 | CYP1A2 (0.43) | PLA2G6MAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10685434 | 0.81 | IDO1 (0.53) | PLA2G6MAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15874768 | 0.80 | CYP19A1 (0.52) | PLA2G6MAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15874769 | 0.80 | CYP19A1 (0.52) | PLA2G6MAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8640805 | 0.76 | CYP1A2 (0.50) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL11442085 | 0.76 | ALDH1A1 (0.44) | MAPK1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL6140008 | 0.75 | ALDH1A1 (0.41) | PLA2G6MAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29853558 | 0.75 | GID4 (0.52) | MAPK1ALDH1A1HPGDSMN1; SMN2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | claimed |
| US-20070078121-A1 | Enzyme modulators and treatments | DECIPHERA PHARMACEUTICALS, LLC | 2007-04-05 | — | — | US | claimed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | claimed |
| CN-110072842-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-107105657-A | Molecule and relative intermediate, composition and method with desinsection effectiveness | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| US-8846019-B2 | Use of protoberberines as an active substance regulating the pilosebaceous unit | SEDERMA (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8591874-B2 | Inhibition of mammalian hair growth | THE PROCTER & GAMBLE COMPANY (US) | 2013-11-26 | — | — | US | disclosed |
| US-8481015-B2 | Applying agmatine and a dermatologically acceptable carrier to the skin; inhibiting hair growth | THE PROCTER & GAMBLE COMPANY (US) | 2013-07-09 | — | — | US | disclosed |
| US-8163756-B2 | For example,1-(3-t-butyl-1- (1,2,3,4-tetrahydro- isoquinolin-6-yl)-1H- pyrazol-5-yl)-3-(3- cyanophenyl)urea; for treatment of mammalian cancers and inflammatory diseases including rheumatoid arthritis, retinopathies | DECIPHERA PHARMACEUTICALS, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| CN-1756527-B | Regulation of mammalian hair growth | PROCTER & GAMBLE | 2010-12-08 | — | — | CN | disclosed |
| US-20090269395-A1 | USE OF PROTOBERBERINES AS AN ACTIVE SUBSTANCE REGULATING THE PILOSEBACEOUS UNIT | SEDERMA (FR) | 2009-10-29 | — | — | US | disclosed |
| EP-1601340-A2 | REGULATION OF MAMMALIAN HAIR GROWTH | THE PROCTER & GAMBLE COMPANY (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2005110353-A1 | PERSONAL CARE COMPOSITIONS AND METHODS FOR REGULATING MAMMALIAN HAIR GROWTH AND SKIN CONDITION | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005110352-A1 | PERSONAL CARE COMPOSITIONS AND METHODS REGULATING MAMMALIAN GROWTH | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050255059-A1 | Personal care compositions and methods regulating mammalian hair growth | PROCTER & GAMBLE COMPANY, THE | 2005-11-17 | — | — | US | disclosed |
| US-20050255060-A1 | Personal care compositions and methods regulating mammalian hair growth | PROCTER & GAMBLE COMPANY, THE | 2005-11-17 | — | — | US | disclosed |
| US-20050245615-A1 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-11-03 | — | — | US | disclosed |
| US-20050003024-A1 | Regulation of mammalian hair growth | THE PROCTER & GAMBLE COMPANY | 2005-01-06 | — | — | US | disclosed |
| WO-2004078157-A2 | REGULATION OF MAMMALIAN HAIR GROWTH | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255059-A1 | Personal care compositions and methods regulating mammalian hair growth | PLOD3, MITF, AADAT | PLA2G6 2811/4885MAPK1 1418/4885ALDH1A1 3562/4885 |
| US-20090269395-A1 | USE OF PROTOBERBERINES AS AN ACTIVE SUBSTANCE REGULATING THE PILOSEBACEOUS UNIT | BROX, CUTA, SHH | PLA2G6 1217/4885MAPK1 3401/4885ALDH1A1 3956/4885 |
| US-20050245615-A1 | Composition containing polyamine transport inhibitor and use thereof | SLC7A1, SRM, SLC16A1 | PLA2G6 2718/4885MAPK1 2388/4885ALDH1A1 1242/4885 |
| US-20070078121-A1 | Enzyme modulators and treatments | ABL1, ABL2, LCK | PLA2G6 2078/4885MAPK1 72/4885ALDH1A1 1036/4885 |
| US-20050255060-A1 | Personal care compositions and methods regulating mammalian hair growth | PCMT1, PLOD3, ARNT | PLA2G6 3219/4885MAPK1 2186/4885ALDH1A1 3085/4885 |
| US-20050003024-A1 | Regulation of mammalian hair growth | BHMT, UGCG, HNMT | PLA2G6 1909/4885MAPK1 636/4885ALDH1A1 3099/4885 |
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | PLA2G6 2370/4885MAPK1 43/4885ALDH1A1 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.