Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | CREB1 | P16220 | 1/20 | 0.53 |
| ▸ | POLH | Q9Y253 | 4/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119670 | 0.82 | ABCB1 (0.76) | ADORA3KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL3699175 | 0.82 | ADORA3 (0.71) | ADORA3KDM4EKMT2AHSD17B10ACE2 | |
| SCHEMBL10486570 | 0.81 | ADORA3 (0.63) | ADORA3KDM4EKMT2AHSD17B10CYP3A4 | |
| SCHEMBL27796731 | 0.79 | CREB1 (0.68) | ADORA3KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL28757172 | 0.79 | ADORA3 (0.60) | ADORA3KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL1664122 | 0.78 | ADORA3 (1.00) | ADORA3ACE2ABCB1CREB1KCNA3 | |
| SCHEMBL30741223 | 0.78 | ADORA3 (1.00) | ADORA3ACE2ABCB1CREB1KCNA3 | |
| SCHEMBL9270632 | 0.78 | CYP3A4 (0.74) | ADORA3KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL27556820 | 0.77 | KDM4E (0.60) | ADORA3KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL1663857 | 0.77 | ADORA3 (1.00) | ADORA3KMT2AMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110008-A1 | ANTI-ULCER ACTIVITY OF FLAVONE ANALOGS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |