Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035250 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4HPGDEHMT2HSD17B10 | |
| SCHEMBL7025888 | 0.79 | ALDH1A1 (0.39) | ALDH1A1CYP3A4HPGDEHMT2HSD17B10 | |
| SCHEMBL29840697 | 0.69 | HSD17B10 (0.41) | KDM4EALDH1A1HSD17B10HTTSMN1; SMN2 | |
| SCHEMBL27921097 | 0.68 | KDM4E (0.38) | KDM4EHTTSMN1; SMN2CA12CA1 | |
| SCHEMBL27573843 | 0.66 | KDM4E (0.43) | KDM4EHSD17B10LMNAHTTSMN1; SMN2 | |
| SCHEMBL11742751 | 0.64 | KDM4E (0.42) | KDM4EHSD17B10LMNAHTTSMN1; SMN2 | |
| SCHEMBL1535150 | 0.64 | CA12 (0.37) | KDM4EALDH1A1LMNACA12CA1 | |
| SCHEMBL78979 | 0.64 | — | — | |
| SCHEMBL4160204 | 0.63 | KDM4E (0.45) | KDM4EHSD17B10LMNAHTTSMN1; SMN2 | |
| SCHEMBL11810597 | 0.62 | KDM4E (0.44) | KDM4EHSD17B10LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268935-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | claimed |
| JP-2009501246-A | — | — | 2009-01-15 | — | — | JP | claimed |
| EP-1901778-A2 | PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL, AND FOOD ADDITIVE COMPOUNDS | Elan Pharmaceuticals Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| US-20070021555-A1 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. | 2007-01-25 | — | — | US | claimed |
| WO-2007008563-A2 | PREPARATION OF PEGYLATED CONJUGATES OF VLA-4 ANTAGONISTS VIA A MITSUNOBU' S REACTION | ELAN PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| JP-3043813-B2 | — | — | 2000-05-22 | — | — | JP | claimed |
| US-5847164-A | Method for the preparation of chromanone 7 | SARAWAK MEDICHEM PHARMACEUTICALS, INC. (US) | 1998-12-08 | — | — | US | claimed |
| EP-0775130-A1 | METHOD FOR THE PREPARATION OF (+/-)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1997-05-28 | — | — | EP | claimed |
| WO-1996004263-A1 | METHOD FOR THE PREPARATION OF (±)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1996-02-15 | — | — | WO | claimed |
| US-20140073788-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | ELAN PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8569426-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130018187-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | ELAN PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | US | disclosed |
| US-8268935-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| EP-1901778-A2 | PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL, AND FOOD ADDITIVE COMPOUNDS | Elan Pharmaceuticals Inc. (US) | 2008-03-26 | — | — | EP | disclosed |
| US-5859050-A | ADMINISTERING TO PREVENT OR TREAT A VIRAL INFECTION | SARAWAK MEDICHEM PHARMACEUTICALS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5847164-A | Method for the preparation of chromanone 7 | SARAWAK MEDICHEM PHARMACEUTICALS, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5840921-A | Method for the preparation of aldol product 7B | SARAWAK MEDICHEM PHARMACEUTICALS, INC. (US) | 1998-11-24 | — | — | US | disclosed |
| WO-1998038193-A1 | METHOD FOR THE PREPARATION OF (+)-CALANOLIDE A AND ANALOGUES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1998-09-03 | — | — | WO | disclosed |
| EP-0775130-A1 | METHOD FOR THE PREPARATION OF (+/-)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004263-A1 | METHOD FOR THE PREPARATION OF (±)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073788-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | MANBA, OAT, PIGO | KDM4E 3039/4885ALDH1A1 1425/4885CYP3A4 2057/4885 |
| US-20130018187-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | MANBA, OAT, PIGO | KDM4E 3039/4885ALDH1A1 1425/4885CYP3A4 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.