Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 12/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059363 | 0.81 | HTR3A (0.59) | TLR7NPY1RACP1HTR3A | |
| SCHEMBL4057349 | 0.78 | HTR3A (0.58) | TLR7NPY1RHTR3A | |
| SCHEMBL1376613 | 0.76 | NPC1 (0.44) | HTR3A | |
| SCHEMBL1372736 | 0.75 | HTR3A (0.67) | HTR3A | |
| SCHEMBL1372733 | 0.75 | HTR3A (0.67) | HTR3A | |
| SCHEMBL1372695 | 0.75 | HTR3A (0.64) | HTR3A | |
| SCHEMBL4056938 | 0.74 | HRH3 (0.44) | NPY1RACP1HTR3A | |
| SCHEMBL4057662 | 0.72 | HRH3 (0.61) | — | |
| SCHEMBL4054814 | 0.72 | HRH3 (0.58) | — | |
| SCHEMBL4060869 | 0.72 | HTR3A (0.60) | TLR7NPY1RHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | disclosed |