Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693511 | 0.79 | TRPM8 (0.50) | NR3C2TSHRHDAC1HDAC8HDAC6 | |
| SCHEMBL30626413 | 0.79 | BCL2 (0.47) | PTPN1TSHRHTR2ACALM1BCL2 | |
| SCHEMBL5852076 | 0.79 | BCL2 (0.47) | PTPN1TSHRHTR2ACALM1BCL2 | |
| SCHEMBL1704796 | 0.79 | PTPN1 (0.45) | PTPN1NR3C2TSHRHTR2ACALM1 | |
| SCHEMBL918512 | 0.77 | NR3C2 (0.56) | NR3C2TSHRCALM1HDAC1HDAC8 | |
| SCHEMBL10659836 | 0.76 | BCL2 (0.52) | PTPN1HTR2ACALM1BCL2BCL2L1 | |
| Ammonia Solution, Strong SCHEMBL28750457 | 0.76 | BCL2 (0.44) | PTPN1TSHRHTR2ACALM1BCL2 | |
| SCHEMBL9446230 | 0.75 | NR3C2 (0.59) | NR3C2TSHRHDAC1HDAC8HDAC6 | |
| Bromide SCHEMBL4613403 | 0.75 | NR3C2 (0.55) | NR3C2TSHRCALM1HDAC1HDAC8 | |
| SCHEMBL9116726 | 0.75 | ALDH1A1 (0.45) | NR3C2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141702-B2 | Process for the synthesis of α-substituted acroleins | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-11-28 | — | — | US | claimed |
| US-20050215829-A1 | Tandem hydroformylation and Mannich reaction sequence in the presence of syngas and formaldehyde, wherein the two catalysts are segregated into two different phases to prevent deactivation of the catalysts by each other, and yielding a highly selective and active catalyst; e.g. ethylene to methacrolein | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | claimed |
| WO-2005063668-A1 | PROCESS FOR SYNTHESIS OF ALPHA-SUBSTITUTED ACROLEINS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | claimed |
| EP-2055763-A1 | Lubricating oil composition | Shell Internationale Research Maatschappij B.V. (NL) | 2009-05-06 | — | — | EP | disclosed |
| US-7141702-B2 | Process for the synthesis of α-substituted acroleins | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-11-28 | — | — | US | disclosed |
| US-20050215829-A1 | Tandem hydroformylation and Mannich reaction sequence in the presence of syngas and formaldehyde, wherein the two catalysts are segregated into two different phases to prevent deactivation of the catalysts by each other, and yielding a highly selective and active catalyst; e.g. ethylene to methacrolein | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | disclosed |
| WO-2005063668-A1 | PROCESS FOR SYNTHESIS OF ALPHA-SUBSTITUTED ACROLEINS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |
| EP-0326223-B1 | Copolymer composition | SHELL INT RESEARCH (NL) | 1996-05-08 | — | — | EP | disclosed |
| EP-0458814-A1 | FLUOROPOLYMER COMPOSITIONS | RAYCHEM CORPORATION (US) | 1991-12-04 | — | — | EP | disclosed |
| US-4992499-A | Using phenolic compound and aromatic amine | SHELL OIL COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| WO-1990008805-A1 | FLUOROPOLYMER COMPOSITIONS | RAYCHEM CORPORATION (US) | 1990-08-09 | — | — | WO | disclosed |
| EP-0326223-A2 | Copolymer composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-08-02 | — | — | EP | disclosed |