SCHEMBL4058199

SCHEMBL4058199

CC(C)OC(=O)N1CCC(N(Cc2cnc(-c3ccc(C(N)=O)c(F)c3)cn2)C2CC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4057221 0.92 GPR119 (0.53) GPR119
SCHEMBL4047813 0.88 GPR119 (0.52) GPR119
SCHEMBL13690516 0.86 GPR119 (0.60) GPR119
SCHEMBL4049785 0.81 GPR119 (0.40) GPR119
SCHEMBL13690488 0.80 GPR119 (0.53) GPR119
SCHEMBL4049265 0.80 GPR119 (0.52) GPR119
SCHEMBL4053026 0.80 GPR119 (0.50) GPR119
SCHEMBL4052001 0.80 GPR119 (0.42) GPR119
SCHEMBL4048220 0.79 GPR119 (0.44) GPR119
SCHEMBL4050169 0.78 GPR119 (0.57) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009106561-A1 PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS BIOVITRUM AB (PUBL) (SE) 2009-09-03 WO disclosed
WO-2009106561-A1 PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS BIOVITRUM AB (PUBL) (SE) 2009-09-03 WO disclosed