Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055213 | 0.86 | MAPT (0.48) | MAPTF2RL3ALDH1A1TDP1MEN1 | |
| SCHEMBL4053668 | 0.82 | KDM4E (0.39) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL4062570 | 0.78 | ESRRA (0.37) | MAPT | |
| SCHEMBL4541903 | 0.78 | MYLK (0.40) | MAPTALDH1A1HTTLMNANPSR1 | |
| SCHEMBL4030576 | 0.77 | ALDH1A1 (0.47) | MAPTF2RL3ALDH1A1TDP1MEN1 | |
| SCHEMBL2191809 | 0.76 | TDP1 (0.54) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2813500 | 0.76 | HTT (0.55) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL4026837 | 0.76 | MAPT (0.45) | MAPTF2RL3ALDH1A1TDP1MEN1 | |
| SCHEMBL4053047 | 0.75 | ALDH1A1 (0.39) | MAPTF2RL3ALDH1A1MEN1KMT2A | |
| SCHEMBL10577625 | 0.72 | CDK2 (0.46) | MAPTF2RL3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |