Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 13/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 12/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 12/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4058353 | 0.98 | GNAO1 (0.47) | GNAO1GNAI3GNAI1TSHRTHRB | |
| Water SCHEMBL11594747 | 0.86 | GNAO1 (0.45) | GNAO1GNAI3GNAI1TSHRTHRB | |
| SCHEMBL3815700 | 0.83 | GNAI3 (0.37) | GNAO1GNAI3GNAI1 | |
| SCHEMBL1140661 | 0.81 | GNAI3 (0.40) | GNAO1GNAI3GNAI1 | |
| SCHEMBL7522015 | 0.79 | TSHR (0.47) | GNAO1GNAI3GNAI1TSHRTHRB | |
| SCHEMBL10721819 | 0.79 | TSHR (0.47) | GNAO1GNAI3GNAI1TSHRTHRB | |
| SCHEMBL11873435 | 0.79 | TSHR (0.47) | GNAO1GNAI3GNAI1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL2469834 | 0.77 | TSHR (0.44) | GNAO1GNAI3GNAI1TSHRTHRB | |
| SCHEMBL4905100 | 0.77 | GNAI3 (0.33) | GNAO1GNAI3GNAI1 | |
| SCHEMBL899276 | 0.75 | TSHR (0.42) | GNAO1GNAI3GNAI1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123675-A1 | IMPROVED CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2009-10-08 | — | — | WO | disclosed |