Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741867 | 0.86 | MAOB (0.61) | PTPN1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL4382965 | 0.83 | NAMPT (0.45) | NAMPTMEN1KMT2APPARGMIF | |
| SCHEMBL10644987 | 0.82 | NAMPT (0.58) | NAMPTPTPN1MEN1KMT2AMIF | |
| SCHEMBL7168178 | 0.82 | MAOB (0.56) | PTPN1MEN1KMT2APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL10606782 | 0.81 | F2 (0.57) | NAMPTPTPN1MEN1KMT2APPARG | |
| SCHEMBL2839499 | 0.81 | ITGB3 (0.52) | NAMPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL2837835 | 0.81 | NAMPT (0.48) | NAMPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8614130 | 0.81 | MAOB (0.71) | NAMPTMEN1KMT2APOLBRAB9A | |
| SCHEMBL2832025 | 0.80 | NAMPT (0.49) | NAMPTMEN1KMT2APPARGNPC1 | |
| SCHEMBL2841991 | 0.80 | LMNA (0.49) | NAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061448-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |