Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301583 | 0.88 | TACR1 (0.52) | TACR1 | |
| SCHEMBL6819378 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBALDH1A1LMNAPDE2A | |
| SCHEMBL7982476 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL7744085 | 0.76 | HDAC8 (0.41) | TACR1PDE2AHDAC8 | |
| SCHEMBL6816712 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL6811708 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL7737905 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL3299439 | 0.75 | TACR1 (0.49) | ALDH1A1TACR1 | |
| SCHEMBL11512864 | 0.72 | MAPT (0.49) | SMN1; SMN2ALDH1A1LMNATACR1HDAC8 | |
| SCHEMBL3298749 | 0.71 | MAPT (0.56) | SMN1; SMN2POLBALDH1A1LMNATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074085-A2 | ANTI-INFECTIVE THIOUREA COMPOUNDS | Lica Pharmaceuticals A/S (DK) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008043840-A2 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2008-04-17 | — | — | WO | disclosed |