Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145697 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| SCHEMBL2825758 | 0.76 | CA12 (0.52) | ALDH1A1CYP2C9CA12CA1CA2 | |
| SCHEMBL1848393 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| Acrylamide SCHEMBL3627369 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| Dimethylformamide SCHEMBL28236645 | 0.73 | THRB (0.50) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| SCHEMBL9472770 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| SCHEMBL9209842 | 0.73 | GLO1 (0.37) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| SCHEMBL3766346 | 0.72 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| SCHEMBL15158243 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2C9NPSR1GLO1 | |
| SCHEMBL17512917 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2C9NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109659-A2 | DISPERSANT COMBINATION FOR IMPROVED TRANSMISSION FLUIDS | The Lubrizol Corporation (US) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008094781-A2 | DISPERSANT COMBINATION FOR IMPROVED TRANSMISSION FLUIDS | THE LUBRIZOL CORPORATION (US) | 2008-08-07 | — | — | WO | disclosed |