Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683356 | 0.90 | KMT2A (0.50) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL4058318 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EUSP2SMN1; SMN2MAPT | |
| SCHEMBL4055614 | 0.86 | KMO (0.49) | ALDH1A1MAPTHPGDKMT2APKM | |
| SCHEMBL4056676 | 0.77 | KDM4E (0.49) | KDM4ESMN1; SMN2MAPTL3MBTL1HPGD | |
| SCHEMBL4060030 | 0.74 | HDAC2 (0.49) | — | |
| SCHEMBL4052576 | 0.73 | KMO (0.45) | ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1 | |
| SCHEMBL2047793 | 0.72 | HPGD (0.63) | ALDH1A1KDM4EUSP2SMN1; SMN2MAPT | |
| SCHEMBL4064114 | 0.72 | PTPN1 (0.54) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL30738654 | 0.72 | RAB9A (0.73) | ALDH1A1SMN1; SMN2L3MBTL1KMT2ANPC1 | |
| SCHEMBL4318071 | 0.71 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EUSP2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |