Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL10565823 | 0.80 | LMNA (0.48) | KDM4ESMN1; SMN2MAPTL3MBTL1WDR5 | |
| SCHEMBL4060036 | 0.77 | ALDH1A1 (0.47) | KDM4ESMN1; SMN2MAPTL3MBTL1RAB9A | |
| SCHEMBL13887202 | 0.77 | PDCD1 (0.49) | KDM4ESMN1; SMN2MAPTWDR5MKNK1 | |
| SCHEMBL4064114 | 0.76 | PTPN1 (0.54) | SMN1; SMN2RAB9ANPC1PTPN1MEN1 | |
| Biphenyl SCHEMBL5494233 | 0.75 | MAPT (0.52) | KDM4ESMN1; SMN2MAPTL3MBTL1WDR5 | |
| SCHEMBL2455360 | 0.75 | SMN1; SMN2 (0.52) | KDM4ESMN1; SMN2MAPTL3MBTL1WDR5 | |
| SCHEMBL8767173 | 0.74 | ALDH1A1 (0.41) | HPGDKMT2A | |
| SCHEMBL29672410 | 0.74 | LMNA (0.55) | KDM4ESMN1; SMN2MAPTHPGDMEN1 | |
| SCHEMBL4058318 | 0.74 | SMN1; SMN2 (0.49) | KDM4ESMN1; SMN2MAPTL3MBTL1RAB9A | |
| SCHEMBL19802884 | 0.73 | WDR5 (0.60) | KDM4ESMN1; SMN2MAPTL3MBTL1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |