Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4060090

CC1=Cc2c(-c3ccccc3)cccc2C1[Ti+2].[Cl-].[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
BRD4 O60885 1/20 0.32
CYP2A6 P11509 2/20 0.31
USP30 Q70CQ3 1/20 0.31
CYP2B6 P20813 1/20 0.31
ALDH1A1 P00352 3/20 0.31
ADRA2A P08913 3/20 0.31
HSD17B10 Q99714 2/20 0.31
ADRA2B P18089 2/20 0.31
ADRA2C P18825 2/20 0.31
HPGD P15428 1/20 0.31
BCL2L1 Q07817 1/20 0.31
MAPK1 P28482 1/20 0.31
TNF P01375 1/20 0.30
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL27501648 0.98 PDCD1 (0.34) PDCD1CD274CHRNB2CHRNA4BRD4
Iodide SCHEMBL27476829 0.97 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
Bromide SCHEMBL27463822 0.97 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL28550963 0.81 PDCD1 (0.36) PDCD1CD274CHRNB2CHRNA4BRD4
Hydrochloric Acid SCHEMBL3163965 0.80 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL5084813 0.80 PDCD1 (0.39) PDCD1CD274CHRNB2CHRNA4BRD4
Hydrochloric Acid SCHEMBL5709139 0.80 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
Hydrochloric Acid SCHEMBL29424591 0.80 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
Hydrochloric Acid SCHEMBL4079019 0.80 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
Hydrochloric Acid SCHEMBL5709184 0.80 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0883623-A4 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENT CO (US) 2000-06-28 EP claimed
EP-0883623-A1 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENTIFIC COMPANY (US) 1998-12-16 EP claimed
WO-1998022477-A1 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENTIFIC COMPANY (US) 1998-05-28 WO claimed
WO-2012063972-A1 METHOD FOR COATING REACTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-18 WO disclosed
WO-2009131081-A1 RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-29 WO disclosed
WO-2009116656-A1 PREPOLYMERIZATION CATALYST COMPONENT AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-24 WO disclosed
CN-101525395-A Processes for producing a catalyst component for addition polymerization, a catalyst and an addition polymer SUMITOMO CHEMICAL CO 2009-09-09 CN disclosed
WO-2009104782-A1 ETHYLENE HOMOPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104783-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104785-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
CN-101429257-A Modified particle and its manufacturing method, carrier, catalyst component for addition polymerization, catalyst for addition polymerization and manufacturing method of addition polymer SUMITOMO CHEMICAL CO (JP) 2009-05-13 CN disclosed
CN-1496996-A Modified granular, addition polymerized catalyst composition, addition polymerization catalyst and method of producing addition polymerization product ס�ѻ�ѧ��ҵ��ʽ���� 2004-05-19 CN disclosed
CN-1422286-A Modified particle, support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2003-06-04 CN disclosed
EP-0883623-B1 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENT CO (US) 2003-03-05 EP disclosed
CN-1386765-A Process for producing vinyl compound polymer SUMITOMO CHEMICAL CO (JP) 2002-12-25 CN disclosed
EP-0883623-A4 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENT CO (US) 2000-06-28 EP disclosed
CN-1239482-A Catalysts for polymerization of olefins, process for prodn. of olefin polymers, and processes for prodn. of styrene polymers IDEMITSU PETROCHEMICAL CO (JP) 1999-12-22 CN disclosed
EP-0883623-A1 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENTIFIC COMPANY (US) 1998-12-16 EP disclosed
US-5847176-A Preparation of chiral titanocenes BOULDER SCIENTIFIC COMPANY (US) 1998-12-08 US disclosed
WO-1998022477-A1 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENTIFIC COMPANY (US) 1998-05-28 WO disclosed