Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5709139 | 1.00 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL29424589 | 1.00 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL27772682 | 0.89 | SYK (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27772581 | 0.83 | HTR7 (0.32) | HTR7 | |
| Hydrochloric Acid SCHEMBL31255983 | 0.83 | KIF11 (0.34) | BRD4ALDH1A1 | |
| SCHEMBL7030356 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL5709184 | 0.80 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL29424591 | 0.80 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL3163965 | 0.80 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL27537901 | 0.80 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539478-A | Preparation method of comb-shaped polyolefin thermoplastic elastomer based on feeding strategy regulation and control | 浙江大学衢州研究院 | 2022-05-27 | — | — | CN | claimed |
| EP-2291419-B1 | POLYMACROMONOMER AND PROCESS FOR PRODUCTION THEREOF | EXXONMOBIL CHEM PATENTS INC (US) | 2013-08-21 | — | — | EP | claimed |
| US-20120309903-A1 | Polymacromonomer and Process For Production Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-12-06 | — | — | US | claimed |
| US-8283428-B2 | Polymacromonomer and process for production thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-09 | — | — | US | claimed |
| US-20090318640-A1 | Polymacromonomer And Process For Production Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-12-24 | — | — | US | claimed |
| WO-2009155510-A2 | POLYMACROMONOMER AND PROCESS FOR PRODUCTION THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-12-23 | — | — | WO | claimed |
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | claimed |
| CN-1705688-A | Multi-catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEM PATENTS INC (US) | 2005-12-07 | — | — | CN | claimed |
| EP-1558655-A2 | MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM | Exxonmobil Chemical Patents Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | claimed |
| WO-2004046214-A2 | MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-06-03 | — | — | WO | claimed |
| CN-110305605-B | Adhesive compositions made from propylene-based polymers and crystalline C2/C3 homopolymers | 埃克森美孚化学专利公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-113544173-A | Olefin resin, crosslinked product thereof, and processes for producing the same | 三井化学株式会社 | 2021-10-22 | — | — | CN | disclosed |
| CN-107922537-B | Preparation of multiphase polymers in gas or slurry phase | 埃克森美孚化学专利公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-107109000-B | Heat activated fabrics made from blends containing propylene-based polymers | 埃克森美孚化学专利公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-1152897-C | Propylene/ethylene-a-olefin block copolymer and process for producing the same | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1274359-A | Mu-oxometallocene complex compound, and olefin polymerization catalyst and polymerization method using same | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1274360-A | Processes for prepn. of metallocene complexes | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1239482-A | Catalysts for polymerization of olefins, process for prodn. of olefin polymers, and processes for prodn. of styrene polymers | IDEMITSU PETROCHEMICAL CO (JP) | 1999-12-22 | — | — | CN | disclosed |
| CN-1170008-A | Propylene/ethylene-a-olefin block copolymer and process for producing the same | SUMITOMO CHEMICAL CO (JP) | 1998-01-14 | — | — | CN | disclosed |