SCHEMBL4060096

SCHEMBL4060096

CCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.79
TP53 P04637 1/20 0.70
TSHR P16473 1/20 0.70
PLA2G4B P0C869 6/20 0.68
PKM P14618 1/20 0.62
PLA2G4A P47712 1/20 0.60
MAPK1 P28482 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
PLK1 P53350 1/20 0.60
HTT P42858 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175191 0.94 TP53 (0.77) RARBTP53TSHRPLA2G4BPKM
SCHEMBL8081583 0.93 RARB (0.90) RARBTP53TSHRPLA2G4BPKM
SCHEMBL7336812 0.93 RARB (0.90) RARBTP53TSHRPLA2G4BPKM
Hydrochloric Acid SCHEMBL6560957 0.93 TP53 (0.74) RARBTP53TSHRPLA2G4BPKM
SCHEMBL2356103 0.92 RARB (0.68) RARBTP53TSHRPLA2G4BPKM
SCHEMBL3074389 0.90 RARB (0.97) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL2490183 0.90 RARB (0.97) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL13828471 0.89 RARB (0.83) RARBTP53TSHRPLA2G4BPKM
SCHEMBL8569877 0.89 PKM (0.78) RARBTP53TSHRPLA2G4BPKM
SCHEMBL4185457 0.88 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2727947-B1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT THEREOF DAINIPPON INK & CHEMICALS (JP) 2017-03-15 EP disclosed
EP-2555046-B1 POLYMER FOR USE IN A LIQUID-CRYSTAL ALIGNMENT LAYER DAINIPPON INK & CHEMICALS (JP) 2015-12-09 EP disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
US-6331521-B1 BETA-1,3-GLUCAN SYNTHASE INHIBITORS; PNEUMOCYSTIS PNEUMONIA INFECTION TREATMENT; FUNGICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-12-18 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
EP-0983297-A1 NEW ECHINOCANDINE DERIVATIVES WITH ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-03-08 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
WO-1998052967-A1 NEW ECHINOCANDIDE DERIVATIVES WITH ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-11-26 WO disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed
US-4225454-A Ortho-cyanophenyl biphenylcarboxylate liquid crystal esters and mixtures thereof HUGHES AIRCRAFT COMPANY (US) 1980-09-30 US disclosed
US-4136053-A BIPHENYL ESTERS AND LIQUID CRYSTALLINE MIXTURES COMPRISING THEM MERCK PATENT GESELLSCHAFT MIT BESCHANKTER HAFTUNG (DE) 1979-01-23 US disclosed
US-4065489-A Biphenyl esters and liquid crystalline mixtures comprising them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM RARB 142/4885TP53 4770/4885TSHR 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.