Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057493 | 0.88 | PSMB5 (0.41) | PSMB5TRPV1CES2CES1MAPT | |
| SCHEMBL5582408 | 0.81 | CES2 (0.44) | TRPV1CES2CES1MAPTGPR84 | |
| SCHEMBL108545 | 0.81 | CES1 (0.48) | CES2CES1MAPTALDH1A1TP53 | |
| SCHEMBL14533069 | 0.79 | GPR84 (0.53) | TRPV1CES2CES1GPR84FFAR4 | |
| SCHEMBL10765419 | 0.79 | GPR84 (0.53) | TRPV1CES2CES1GPR84FFAR4 | |
| SCHEMBL4057035 | 0.79 | TDP1 (0.41) | PSMB5ALDH1A1 | |
| SCHEMBL21596744 | 0.79 | CES1 (0.46) | CES2CES1MAPTALDH1A1TP53 | |
| SCHEMBL9699354 | 0.77 | KMT2A (0.45) | CES2CES1MAPTALDH1A1TP53 | |
| SCHEMBL8594270 | 0.76 | CES1 (0.48) | CES2CES1MAPTGPR84ALDH1A1 | |
| SCHEMBL2049922 | 0.76 | CES1 (0.48) | CES2CES1MAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |