Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18684491 | 0.86 | CES2 (0.39) | CES2CES1TRPV1ALDH1A1GPR84 | |
| SCHEMBL14533069 | 0.84 | GPR84 (0.53) | CES2CES1TRPV1GPR84FFAR4 | |
| SCHEMBL10765419 | 0.84 | GPR84 (0.53) | CES2CES1TRPV1GPR84FFAR4 | |
| SCHEMBL8594270 | 0.81 | CES1 (0.48) | CES2CES1ALDH1A1TP53GPR84 | |
| SCHEMBL4060468 | 0.81 | PSMB5 (0.41) | CES2CES1TRPV1ALDH1A1TP53 | |
| SCHEMBL29049624 | 0.80 | SLC22A6 (0.38) | GPR84MAPT | |
| SCHEMBL25674836 | 0.79 | TRPV1 (0.39) | CES2CES1TRPV1ALDH1A1TP53 | |
| SCHEMBL21596744 | 0.79 | CES1 (0.46) | CES2CES1ALDH1A1TP53MAPT | |
| Valeric Acid SCHEMBL1124409 | 0.78 | GPR84 (0.57) | ALDH1A1GPR84KMT2AFFAR4FFAR1 | |
| SCHEMBL6064469 | 0.78 | GPR84 (0.52) | CES2CES1TRPV1GPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105197-A1 | Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from Comamonas testosteroni 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids | PAYNE MARK S | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105197-A1 | Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from Comamonas testosteroni 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids | NAAA, MGAM2, MGAM | CES2 1209/4885CES1 377/4885TRPV1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.