Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060733 | 1.00 | ENPP2 (0.48) | ENPP2CISD1KMT2AMEN1POLB | |
| SCHEMBL4054938 | 0.88 | KMT2A (0.40) | ENPP2CISD1KMT2AMEN1POLB | |
| SCHEMBL4054942 | 0.88 | KMT2A (0.40) | ENPP2CISD1KMT2AMEN1POLB | |
| SCHEMBL4052876 | 0.86 | PTPN1 (0.49) | ENPP2CISD1POLBHPGDPTPN1 | |
| SCHEMBL4052873 | 0.86 | PTPN1 (0.49) | ENPP2CISD1POLBHPGDPTPN1 | |
| SCHEMBL4054941 | 0.83 | HPGD (0.48) | KMT2AMEN1MAPTHPGDPTPN1 | |
| SCHEMBL4054943 | 0.83 | HPGD (0.48) | KMT2AMEN1MAPTHPGDPTPN1 | |
| SCHEMBL4053340 | 0.80 | PTPN1 (0.40) | ENPP2HPGDPTPN1 | |
| SCHEMBL4053337 | 0.80 | PTPN1 (0.40) | ENPP2HPGDPTPN1 | |
| SCHEMBL4050515 | 0.80 | HPGD (0.48) | POLBHPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |