Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915034 | 0.91 | MAPT (0.48) | MAPTKDM4ETP53HSD17B10ALOX15 | |
| SCHEMBL5724043 | 0.70 | CYP1A1 (0.48) | MAPTKDM4ETP53HSD17B10ALOX15 | |
| SCHEMBL10824405 | 0.65 | PLA2G2A (0.50) | MAPTKDM4ETP53HSD17B10ALOX15 | |
| SCHEMBL7905163 | 0.63 | TP53 (0.46) | MAPTKDM4ETP53HSD17B10ALOX15 | |
| SCHEMBL14973674 | 0.63 | MAPT (0.51) | MAPTKDM4ETP53HSD17B10ALOX15 | |
| Flavone SCHEMBL29178582 | 0.63 | TNKS (0.84) | MAPTKDM4ETP53HSD17B10SMN1; SMN2 | |
| Flavone SCHEMBL110027 | 0.63 | TNKS (0.84) | MAPTKDM4ETP53HSD17B10SMN1; SMN2 | |
| SCHEMBL3878827 | 0.62 | NPC1 (0.55) | MAPTKDM4ETP53HSD17B10SMN1; SMN2 | |
| SCHEMBL15960091 | 0.62 | ALDH1A1 (0.51) | MAPTKDM4EHPGDALOX12PTGS2 | |
| SCHEMBL24227267 | 0.62 | PLA2G2A (0.66) | MAPTKDM4ETP53HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110008-A1 | ANTI-ULCER ACTIVITY OF FLAVONE ANALOGS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |