Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TNKS | O95271 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915034 | 0.77 | MAPT (0.48) | CYP1A1CYP1A2CYP3A4HPGDCYP1B1 | |
| SCHEMBL6039103 | 0.76 | CYP1B1 (0.47) | CYP1A1CYP1A2CYP3A4HPGDCYP1B1 | |
| SCHEMBL10824405 | 0.71 | PLA2G2A (0.50) | CYP1A1CYP1A2CYP3A4HPGDCYP1B1 | |
| SCHEMBL10810958 | 0.71 | KDM4E (0.41) | CYP1A1CYP1A2CYP3A4HPGDCYP1B1 | |
| SCHEMBL3520877 | 0.71 | CYP3A4 (0.50) | CYP1A1CYP1A2CYP3A4HPGDCYP1B1 | |
| Acetamide SCHEMBL4060765 | 0.70 | MAPT (0.44) | CYP1A1CYP1A2CYP3A4HPGDCYP1B1 | |
| SCHEMBL26249669 | 0.69 | PRKDC (0.39) | CYP1A1CYP1A2HPGDCYP1B1TP53 | |
| SCHEMBL26267707 | 0.69 | PRKDC (0.39) | CYP1A1CYP1A2HPGDCYP1B1TP53 | |
| SCHEMBL18714133 | 0.68 | CYP1A1 (0.32) | CYP1A1CYP1A2CYP1B1RAB9AALDH1A1 | |
| SCHEMBL30064082 | 0.67 | MAOA (0.50) | CYP3A4HPGDCYP1B1ARTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075162-A | Crystal form B of 7, 8-dihydroxyflavone derivative, and preparation method and application thereof | 上海博芮健制药有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-111825649-A | Purification method of 7,8-dihydroxyflavone derivative | 上海博芮健制药有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-2008016838-A1 | TOPICAL SKIN COMPOSITIONS, THEIR PREPARATION AND THEIR USE | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2008-02-07 | — | — | WO | disclosed |
| EP-1077697-B1 | METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE | ENDOWMENT FOR RES IN HUMAN BIO (US) | 2006-07-19 | — | — | EP | disclosed |