Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239069 | 0.89 | GSK3B (0.61) | GSK3BDYRK1B | |
| SCHEMBL39137 | 0.89 | GSK3B (0.61) | GSK3BDYRK1B | |
| SCHEMBL22801094 | 0.88 | KAT6A (0.56) | KAT6AXDHCLK4CTSSCTSK | |
| SCHEMBL20647100 | 0.88 | MAPT (0.56) | KAT6AXDHSLC22A12CLK4PTPN5 | |
| SCHEMBL5529069 | 0.84 | XDH (0.62) | KAT6AXDHSLC22A12CLK4GSK3B | |
| SCHEMBL10389918 | 0.83 | MAP4K4 (0.59) | CLK4MAP4K4CSNK1G2MKNK2MAP4K5 | |
| SCHEMBL7822720 | 0.82 | PLAU (0.61) | KAT6AXDHSLC22A12GSK3BCDK8 | |
| SCHEMBL16108317 | 0.81 | KAT6A (0.59) | KAT6AXDHSLC22A12CLK4GSK3B | |
| SCHEMBL2586835 | 0.81 | KMO (0.59) | CLK4MAP4K4CSNK1G2MKNK2MAP4K5 | |
| SCHEMBL254013 | 0.81 | XDH (0.54) | KAT6AXDHSLC22A12CLK4GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |