SCHEMBL406210

SCHEMBL406210

CSc1ccc(-c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 3/20 0.47
ALOX12 P18054 1/20 0.47
PTGS2 P35354 4/20 0.46
PTGS1 P23219 1/20 0.46
ACHE P22303 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HAO1 Q9UJM8 1/20 0.41
NISCH Q9Y2I1 1/20 0.41
ALDH1A3 P47895 1/20 0.41
CYP17A1 P05093 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19110965 1.00 MAPT (0.50) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL19107726 0.93 MEN1 (0.46) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL17914390 0.93 MEN1 (0.46) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL76792 0.91
Hydrochloric Acid SCHEMBL7990919 0.88 MEN1 (0.54) MAPTNPC1RAB9AMEN1KMT2A
Water SCHEMBL27813433 0.88 MEN1 (0.54) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL10528160 0.88 ALDH1A1 (0.50) ALDH1A1PTGS2PTGS1HAO1NISCH
SCHEMBL10300271 0.88 ALDH1A1 (0.50) ALDH1A1PTGS2PTGS1HAO1NISCH
SCHEMBL12533886 0.87 MEN1 (0.42) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL8736741 0.83 MEN1 (0.50) MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911974-B2 Metal/resin composite structure and method for manufacturing same DIC CORPORATION (JP) 2024-02-27 US disclosed
US-11911974-B2 Metal/resin composite structure and method for manufacturing same DIC CORPORATION (JP) 2024-02-27 US disclosed
EP-4306591-A1 POLYARYLENE SULFIDE RESIN COMPOSITION, MOLDED ARTICLE, AND METHODS RESPECTIVELY FOR PRODUCING SAID POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2024-01-17 EP disclosed
US-20230364836-A1 FORCED EXTRACTION MOLDED ARTICLE, POLYARYLENE SULFIDE RESIN COMPOSITION, AND METHOD FOR PRODUCING FORCED EXTRACTION MOLDED ARTICLE DIC CORPORATION (JP) 2023-11-16 US disclosed
US-20230364836-A1 FORCED EXTRACTION MOLDED ARTICLE, POLYARYLENE SULFIDE RESIN COMPOSITION, AND METHOD FOR PRODUCING FORCED EXTRACTION MOLDED ARTICLE DIC CORPORATION (JP) 2023-11-16 US disclosed
US-20230340253-A1 RESIN COMPOSITION AND SHAPED ARTICLE KURARAY CO., LTD. (JP) 2023-10-26 US disclosed
US-11766836-B2 Metal-resin composite and method for producing same DIC CORPORATION (JP) 2023-09-26 US disclosed
US-11766836-B2 Metal-resin composite and method for producing same DIC CORPORATION (JP) 2023-09-26 US disclosed
US-20230295378-A1 POLYARYLENE SULFIDE RESIN COMPOSITION, MOLDED ARTICLE, AND METHODS FOR PRODUCING SAID POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2023-09-21 US disclosed
US-20230295378-A1 POLYARYLENE SULFIDE RESIN COMPOSITION, MOLDED ARTICLE, AND METHODS FOR PRODUCING SAID POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2023-09-21 US disclosed
EP-1978059-A1 HEAT-RESISTANT RESIN COMPOSITION, METHOD FOR PRODUCTION THEREOF, HEAT-RESISTANT RESIN MOLDED ARTICLE, AND SURFACE-MOUNT ELECTRONIC ELEMENT DIC Corporation (JP) 2008-10-08 EP disclosed
US-20080161453-A1 Polyphenylene Sulfide Resin Composition and Plastic Mold Produced Using the Same CHEIL INDUSTRIES INC. (KR) 2008-07-03 US disclosed
US-20080161453-A1 Polyphenylene Sulfide Resin Composition and Plastic Mold Produced Using the Same CHEIL INDUSTRIES INC. (KR) 2008-07-03 US disclosed
EP-1911793-A1 POLYPHENYLENE SULFIDE RESIN STRUCTURE DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-04-16 EP disclosed
US-20080085975-A1 Graft Copolymer, Method For Producing The Same And Resin Composition Containing The Graft Copolymer KANEKA CORPORATION (JP) 2008-04-10 US disclosed
US-20070299219-A1 Biaxially Oriented Polyarylene Sulfide Film and Laminated Polyarylene Sulfide Sheets Comprising the Same TORAY INDUSTRIES, INC. (JP) 2007-12-27 US disclosed
US-20070299219-A1 Biaxially Oriented Polyarylene Sulfide Film and Laminated Polyarylene Sulfide Sheets Comprising the Same TORAY INDUSTRIES, INC. (JP) 2007-12-27 US disclosed
US-20070123627-A1 Polyarylene sulfide thermoplastic resin composition LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2007-05-31 US disclosed
US-20070066736-A1 Resin composition for reflecting plates OTSUKA CHEMICAL CO., LTD. (JP) 2007-03-22 US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds PPA1, PNP, PPME1 MAPT 1076/4885NPC1 626/4885RAB9A 2543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.