Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570796 | 0.85 | MITF (0.49) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL4062335 | 0.85 | MITF (0.50) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL1594228 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL2445825 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL28290761 | 0.70 | MITF (0.62) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL31614495 | 0.70 | MITF (0.52) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL2572021 | 0.69 | MITF (0.42) | ALDH1A1MITFKMT2APOLBMAPT | |
| SCHEMBL1080487 | 0.69 | MITF (0.54) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL12519216 | 0.69 | ALDH1A1 (0.51) | ALDH1A1MITFPKMKMT2ASOS1 | |
| SCHEMBL30211422 | 0.68 | MITF (0.56) | ALDH1A1MITFPKMKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853582-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO KG (DE) | 2009-10-21 | — | — | EP | disclosed |
| EP-1853582-A2 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AiCuris GmbH & Co. KG (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006089664-A2 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2006-08-31 | — | — | WO | disclosed |