Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290784 | 0.89 | ALDH1A1 (0.53) | MITFALDH1A1PKMKMT2ASOS1 | |
| SCHEMBL28290789 | 0.88 | ALDH1A1 (0.57) | MITFALDH1A1PKMKMT2ASOS1 | |
| SCHEMBL28290787 | 0.84 | ALDH1A1 (0.54) | MITFALDH1A1PKMKMT2ASOS1 | |
| SCHEMBL4058834 | 0.83 | ALDH1A1 (0.62) | MITFALDH1A1PKMKMT2ASOS1 | |
| SCHEMBL2962063 | 0.80 | LMNA (0.50) | MITFALDH1A1PKMKMT2ATNF | |
| SCHEMBL13431485 | 0.79 | ALDH1A1 (0.75) | MITFALDH1A1PKMKMT2ASOS1 | |
| SCHEMBL28290763 | 0.78 | MITF (0.52) | MITFALDH1A1PKMKMT2ATNF | |
| SCHEMBL3504600 | 0.78 | ALDH1A1 (0.68) | MITFALDH1A1PKMKMT2ASOS1 | |
| SCHEMBL28334488 | 0.78 | ALDH1A1 (0.68) | MITFALDH1A1PKMKMT2ASOS1 | |
| SCHEMBL14181603 | 0.78 | ALDH1A1 (0.73) | MITFALDH1A1PKMKMT2ASOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109706198-A | A kind of method that online enzyme process closes nitro imidazole derivatives | 浙江工业大学 | 2019-05-03 | — | — | CN | disclosed |