Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 7/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062237 | 1.00 | DHODH (0.43) | DHODHALDH1A1ALDH1A3ALDH1A2NPC1 | |
| SCHEMBL4067972 | 0.87 | HSD17B10 (0.33) | ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4067977 | 0.87 | HSD17B10 (0.33) | ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4063303 | 0.85 | KDM4E (0.34) | ALDH1A1NPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL4063309 | 0.85 | KDM4E (0.34) | ALDH1A1NPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL4067747 | 0.85 | KDM4E (0.36) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL4067744 | 0.85 | KDM4E (0.36) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL4071056 | 0.85 | KDM4E (0.36) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL4066124 | 0.84 | HTR4 (0.37) | — | |
| SCHEMBL4066121 | 0.84 | HTR4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041153-B1 | NEW 5-THIOXYLOPYRANOSE DERIVATIVES | FOURNIER LAB SA (FR) | 2009-10-21 | — | — | EP | disclosed |