Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063303 | 1.00 | KDM4E (0.34) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4071056 | 0.89 | KDM4E (0.36) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4067747 | 0.89 | KDM4E (0.36) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4067744 | 0.89 | KDM4E (0.36) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4062239 | 0.85 | DHODH (0.43) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4062237 | 0.85 | DHODH (0.43) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4067977 | 0.85 | HSD17B10 (0.33) | KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL4067972 | 0.85 | HSD17B10 (0.33) | KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL4066124 | 0.84 | HTR4 (0.37) | — | |
| SCHEMBL4066121 | 0.84 | HTR4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041153-B1 | NEW 5-THIOXYLOPYRANOSE DERIVATIVES | FOURNIER LAB SA (FR) | 2009-10-21 | — | — | EP | disclosed |